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Martin E. Zuzulo to guide drug development operations for preclinical-stage biotech company


RIEHEN, SWITZERLAND, April 11, 2023 – Ymmunobio, a preclinical stage biotech company specializing in the development of innovative treatments for cancer patients, announced today that it has appointed Martin E. Zuzulo as its new Chief Operating Officer. Zuzulo steps in for Interim COO Peter Schiemann, PhD, who remains as Chairman of the Board for Ymmunobio.



“Marty’s substantial industry, consulting, and business development experience is a great asset for our team,” said Ymmunobio Founder and CEO Katrin Rupalla. “We’re delighted that he has joined the executive team and will be helping to advance our strategy for our novel and first-in-class antibody research.”


“I’m very impressed with the foundational research that Ymmunobio has undertaken to support its plans for drug development and delivery,” said Zuzulo. “Ymmunobio’s assets are positioned to provide powerful therapies in the fight against cancer, and I’m honored to be a part of this esteemed group.”


Zuzulo’s career has been focused on helping biopharmaceutical and medical device companies improve their R&D capabilities, focusing on their quality, clinical, and regulatory environments, as well as their GxP operations. He previously served in manufacturing and process development roles at Biogen and in executive positions across both industry-specific (Parexel) and life sciences practices at several leading management consulting organizations (IBM, PwC, Accenture).


Zuzulo earned his B.S. and B.A. in Biological Sciences (Biochemical Engineering Minor) and Psychology from Stony Brook University in Stony Brook, NY.


Ymmunobio recently was granted Orphan Drug Designation (ODD) by the US Food & Drug Administration (FDA) for YB-200, a CEACAM1/5 antibody it is studying for the treatment of hepatocellular carcinoma (HCC). “This designation is an important milestone in our development of CEACAM antibodies as anti-cancer treatments,” said Dr. Rupalla. The company has also begun developing the lead, fully humanized and first-in-class NPTXR antibody, YB-800, which has demonstrated anti-tumor activity in vivo and in vitro for solid tumors, including several gastro-intestinal and breast cancers.


To learn more about Ymmunobio’s activities and research, visit the website or reach out to info@ymmuno.bio.


ABOUT YMMUNOBIO

Ymmunobio AG is a preclinical stage oncology biotech company focused on the development of innovative treatments for cancer patients through new classes of antibodies. Those treatments present a large market potential and broad applicability in solid tumors. Ymmunobio is making extensive progress in developing antibodies that have an influence on the immune system by reinstating its immune response to cancers or directly inhibiting cancer cell proliferation. Learn more on Ymmunobio’s website and follow on LinkedIn.



Investor Relations: Dr. Katrin Rupalla, info@ymmuno.bio



Participation in the international program guides startups in creating and developing business traction


RIEHEN, SWITZERLAND, March 8, 2023 ─ Ymmunobio, a preclinical stage biotech company specializing in the development of innovative treatments for cancer patients, announced today that it has been accepted into the Swiss Innovation’s Agency Innosuisse Core Coaching Program, which provides support for startups to create a focused and agile strategy as a way to build and maintain a well-structured organization.


“Our acceptance into Innosuisse Core Coaching is a great opportunity to successfully develop our business approach,” said Ymmunobio CEO Katrin Rupalla, PhD, MBA. “Our goal is to continue growing a sustainable enterprise focused on the development of novel antibodies for the treatment of gastro-intestinal cancers. I’m really looking forward to working with Innosuisse’s coaches.”



The Start-up Coaching program takes place over three years and is aimed at young companies and their founders. It offers three different programs, each focusing on specific development aspects in a way that is tailored to each startup. The company will work with a lead coach and special coaches on such aspects as fundraising, IP, financial planning and legal aspects. Additionally, participants have the opportunity to take part in global trade fairs and will have access to the Milestone Review in order to report and review progress.


Upon completion of the Core Coaching program, Ymmunobio can request the Innosuisse Certificate, which confirms that the startup is ready for sustainable growth.

To learn more about Ymmunobio’s activities and research, visit the website or reach out to info@ymmuno.bio.


ABOUT YMMUNOBIO

Ymmunobio is a preclinical stage oncology biotech company focused on the development of innovative treatments for cancer patients through new classes of antibodies. Those treatments present a large market potential and broad applicability in solid tumors. Ymmunobio is making extensive progress in developing antibodies that have an influence on the immune system by reinstating its immune response to cancers or directly inhibiting cancer cell proliferation. Learn more on Ymmunobio’s website and follow on LinkedIn.



Investor Relations: Dr. Katrin Rupalla, info@ymmuno.bio



Mitsuro Kanda, MD, PhD, and Vishal Khairnar, PhD, join growing biotech company developing antibodies as therapies against various cancers


RIEHEN, SWITZERLAND, March 2, 2023 ─ Ymmunobio, a preclinical stage biotech company specializing in the development of innovative treatments for cancer patients, announced today that Mitsuro Kanda, MD, PhD, Assistant Professor in the Department of Gastroenterological Surgery at Nagoya University Graduate School of Medicine, and Vishal Khairnar, PhD, Senior Scientist, Preclinical research at Cytovia Therapeutics, Inc. MA, USA, have joined the Ymmunobio Advisory Board. Dr. Kanda and Dr. Khairnar will contribute scientific guidance and insights to assist Ymmunobio in advancing its preclinical drug development efforts.



“We are honored that Dr. Kanda and Dr. Khairnar have elected to join our advisory board and support our strategy to develop cancer treatments through the application of novel and first-in-class antibodies,” said Ymmunobio CEO Katrin Rupalla, PhD, MBA. “Their deep experience and understanding of preclinical drug development are invaluable and we’re grateful for their participation.”


“Ymmunobio demonstrates a strong foundation in novel therapeutic antibodies,” said Dr. Kanda. “Together, we will work to advance research into neuronal pentraxin receptor (NPTXR) antibodies, which have shown its potential utility as a target for the development of therapeutic antibodies in gastro-intestinal cancers.”


Dr. Kanda, inventor of NPTXR antibodies, has been an Assistant Professor in the Department of Gastroenterological Surgery at the University of Nagoya School of Medicine in Nagoya, Japan, since 2012. He is an editorial board member of Gastric Cancer, Gastroenterology Research and Practice, Annals of Cancer Research and Therapy, and the Journal of Gastric Cancer. He was awarded the 2009 AACR Annual Meeting Scholar-in-Training Award (ITO-EN). Dr. Kanda completed a postdoctoral fellowship in the Department of Pathology at the Johns Hopkins University. He has identified a variety of novel biomarkers and potential therapeutic targets for solid cancers through translational research using clinical samples. Dr. Kanda received his medical degree from Nagoya University in Japan.


Dr. Khairnar has more than 13 years of research experience in Cellular and Molecular Immunology. “I’m pleased to be able to apply my expertise to support Ymmunobio, especially in the area of CEACAM1 immune agonistic antibodies for the development of precision cancer treatments,” said Dr. Khairnar. “It’s a great research team and I’m looking forward to collaborating to achieve effective cancer therapies.”


Dr. Khairnar found a novel role of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) on the function of B-cells and T-cells upon infection with pathogens. He also proposed and provided proof-of-concept data for the use of anti-human-CEACAM1 antibodies to treat chronic diseases and multiple cancers. As a Senior Scientist at Cytovia Therapeutics, he leads an in vivo group of preclinical researchers to develop and test iPSC derived Natural Killer (NK) cells and bi-specific NK cell engagers for the treatment of hepatocellular carcinoma, multiple myeloma, and other cancers. Dr. Khairnar earned his doctoral degree from the University of Duisburg-Essen in Germany.

Ymmunobio recently signed a transfer ownership agreement with Nagoya University for the license to NPTXR antibodies.


To learn more about Ymmunobio’s activities and research, visit the website or reach out to info@ymmuno.bio.


ABOUT YMMUNOBIO

Ymmunobio is a preclinical stage oncology biotech company focused on the development of innovative treatments for cancer patients through new classes of antibodies. Those treatments present a large market potential and broad applicability in solid tumors. Ymmunobio is making extensive progress in developing antibodies that have an influence on the immune system by reinstating its immune response to cancers or directly inhibiting cancer cell proliferation. Learn more on Ymmunobio’s website and follow on LinkedIn.



Investor Relations: Dr. Katrin Rupalla, info@ymmuno.bio


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